Higher availability and efficacy of protective measures against infectious diseases, such as vaccines, increases individuals’ propensity to socialize. Consequently, the number of visits to central points of interest (e.g., schools, gyms, grocery stores) and the rate of interactions with the agents employed therein (e.g., teachers, trainers, cashiers) increase. This opens more channels for the virus to transmit through the central agent or location. This leads to a manifestation of network hazard (Erol 2019). The infection rates can increase as protective measures become more effective and more available. Testable predictions of the theory are confirmed by the foot traffic data from 2019-2022 and historical COVID-19 vaccination and community transmission rates.